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Scotland Yard said the incident was being treated as "non-suspicious".
A Cabinet Office spokeswoman said: "We can confirm that Alex Allan was taken ill on Monday and transferred to a London hospital.
"We cannot discuss his condition as it is a private matter."
A spokesman for the Metropolitan Police said: "We were made aware of a man in his late 50s who was taken to a London hospital after being taken ill at his home address. He remains in a serious condition. This is being treated as non-suspicious."
The 57-year-old's wife, artist Katie Clemson, died from cancer last November.
Mr Allan reported feeling unwell towards the end of last week and remains in a coma while the hospital conducts tests.
The JIC is part of the Cabinet Office and responsible for briefing the Prime Minister on a weekly basis. Mr Allan was appointed to the position last November. He was previously permanent secretary at the Ministry of Justice.
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